Human iPSC-derived cerebral organoids reveal oxytocin-mediated protection against amyloid-β pathology

Introduction: Neuroinflammation is a key contributor to the pathogenesis of Alzheimer's disease (AD), and impaired clearance of amyloid-β (Aβ) by microglia is closely associated with disease progression. Oxytocin (OXT), a hypothalamic neuropeptide, has recently been reported to exert anti-infla...

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Bibliographic Details
Main Authors: Tomoki Asaba, Sayuri Hamano, Ayaka Nanmo, Jieun Seo, Tatsuto Kageyama, Junji Fukuda
Format: Article
Language:English
Published: Elsevier 2025-12-01
Series:Regenerative Therapy
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Online Access:http://www.sciencedirect.com/science/article/pii/S2352320425001464
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