The crucial role of SPP1 in osteoporosis, osteoarthritis, and cancer
Osteopontin (OPN), also known as secreted phosphoprotein 1(SPP1), is a highly glycosylated and phosphorylated acidic protein, which is a multifunctional glycoprotein expressed in numerous cell types. SPP1 is involved in the attachment of osteoclasts to mineralized bone matrix, inflammatory reaction,...
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| Main Authors: | Yaru Qu, Shuixian Li, Huiyuan Luo, Junnan Li, Tong Wang, Xiuzhen Han |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2025-12-01
|
| Series: | Pharmaceutical Science Advances |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2773216925000121 |
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