Imipenem/cilastatin encapsulation in UIO-66-NH2 carrier as a new strategy for combating imipenem-resistant Pseudomonas aeruginosa isolates

Imipenem/cilastatin encapsulation in UIO-66-NH2 carrier as a new strategy for combating imipenem-resistant Pseudomonas aeruginosa isolates

Background: This study aims to investigate the effectiveness of UIO-66-NH2, a metal-organic framework, as a carrier for imipenem/cilastatin (Imp/Cil) in overcoming resistance in clinical isolates of imipenem-resistant Pseudomonas aeruginosa. Methods: The UIO-66-NH2-Imp/Cil formulations were synthesi...

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Bibliographic Details
Main Authors: Shakila Baei Lashaki, Pooria Moulavi, Fatemeh Ashrafi, Aram Sharifi, Sepideh Asadi
Format: Article
Language:English
Published: Elsevier 2025-05-01
Series:Journal of Global Antimicrobial Resistance
Subjects:
Antibacterial agents
Biofilm
Imipenem/cilastatin
Uio-66-NH2
Pseudomonas aeruginosa
Online Access:http://www.sciencedirect.com/science/article/pii/S2213716525000177
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