Design, synthesis, biological evaluation, and computational insights of 2-(Aryl)benzo[d]imidazo[2,1-b]thiazole-7-sulfonamide derivatives as potent antitubercular and antibacterial agents

Design, synthesis, biological evaluation, and computational insights of 2-(Aryl)benzo[d]imidazo[2,1-b]thiazole-7-sulfonamide derivatives as potent antitubercular and antibacterial agents

Abstract A series of 2-(aryl)benzo[d]imidazo[2,1-b]thiazole-7-sulfonamide derivatives were synthesized and evaluated for their antitubercular and antibacterial activities, molecular docking, and DFT studies. The compounds were synthesized through a multi-step reactions, with yields varying based on...

Full description

Saved in:
Bibliographic Details
Main Authors: Hemant S. Deshmukh, Vishnu A. Adole, Suraj N. Mali, Bapu S. Jagdale
Format: Article
Language:English
Published: BMC 2025-05-01
Series:BMC Chemistry
Subjects:
2-(Aryl)benzo[d]imidazo[2,1-b]thiazole
Sulphonamides
Antitubercular
Antibacterial
Molecular docking
DFT
Online Access:https://doi.org/10.1186/s13065-025-01405-5
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

https://doi.org/10.1186/s13065-025-01405-5

Similar Items