Long-Term Safety Evaluation of Fluorescent Gold Nanoclusters Conjugated with α-Lipoic Acid: Insights from a Six-Month In Vivo Study

Long-Term Safety Evaluation of Fluorescent Gold Nanoclusters Conjugated with α-Lipoic Acid: Insights from a Six-Month In Vivo Study

Background: Fluorescent gold nanoclusters conjugated with α-lipoic acid (FANCs) have shown great promise for drug development. In a previous study, FANCs did not show any acute or subacute toxicity under 0.6–20 μM/100 μL/25 g body weight in male and female ICR mice. However, the chronic toxicity of...

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Main Authors: Yu-Wei Lai, Yi-Nan Lee, Hung-I Yeh, Yih-Jer Wu, Wen-Hsiung Chan, Shih-Wei Wang, Chao-Feng Lin, Chun-Hsuan Lin, Yun-Fang Chen, Ching-Hu Chung
Format: Article
Language:English
Published: MDPI AG 2025-03-01
Series:Journal of Functional Biomaterials
Subjects:
chronic toxicity
fluorescent gold nanoclusters
α-lipoic acid
Online Access:https://www.mdpi.com/2079-4983/16/3/89
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