PCYT2 overexpression induces mitochondrial damage and promotes apoptosis in hepatocellular carcinoma cells.

Phosphatidylethanolamine cytidyltransferase 2 (PCYT2) is commonly regarded as the rate-limiting enzyme in eukaryotic phosphatidylethanolamine synthesis. However, the role of PCYT2 in the development of hepatocellular carcinoma (HCC) unknow. In this study, the role of PCYT2 overexpression in the deve...

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Bibliographic Details
Main Authors: Xu Bei, Caihong Zhao, Jia Liu, Jun Cao, Wanbao Zheng, Tao Wang, Wenjie Lu, Youzhi Xu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2025-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0323974
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