Proteasome caspase-like activity regulates stress granules and proteasome condensates

The 20S proteasome maintains cellular protein homeostasis, particularly during stress responses. In a previous study, we identified numerous 20S proteasome substrates through mass spectrometry analysis of peptides generated from cellular extracts degraded by purified 20S proteasome. Many substrates...

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Bibliographic Details
Main Authors: Shirel Steinberger, Julia Adler, Nadav Myers, Yosef Shaul
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-06-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2025.1570499/full
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