Enrichment factors for clinical trials in mild‐to‐moderate Alzheimer's disease

Abstract Introduction Heterogeneity of outcomes in Alzheimer's disease (AD) clinical trials necessitates large sample sizes and contributes to study failures. This analysis determined whether mild‐to‐moderate AD populations could be enriched for cognitive decline based on apolipoprotein (APOE)...

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Bibliographic Details
Main Authors: Clive Ballard, Alireza Atri, Neli Boneva, Jeffrey L. Cummings, Lutz Frölich, José Luis Molinuevo, Pierre N. Tariot, Lars Lau Raket
Format: Article
Language:English
Published: Wiley 2019-01-01
Series:Alzheimer’s & Dementia: Translational Research & Clinical Interventions
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Online Access:https://doi.org/10.1016/j.trci.2019.04.001
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