Divergent gene expression of PTGS1 and PTGS2 along the disease course of chronic myeloid leukaemia

Divergent gene expression of PTGS1 and PTGS2 along the disease course of chronic myeloid leukaemia

IntroductionChronic myeloid leukaemia (CML) is a chronic myeloproliferative disorder caused by the reciprocal translocation of chromosomes 9 and 22. This genetic abnormality leads to the uncontrolled proliferation of myeloid lineage cells, ultimately causing leukaemia. Inflammation plays a significa...

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Bibliographic Details
Main Authors: Denise K. Wosniaki, Bianca N. Kusma, Anelis M. Marin, Eduardo C. Munhoz, João S. de H. Farias, Eduarda B. Mendes, Mateus N. Aoki, Dalila L. Zanette
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-05-01
Series:Frontiers in Oncology
Subjects:
PTGS1 and PTGS2
inflammatory process
leukaemogenesis
chronic myeloid leukemia
prostaglandin
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2025.1556956/full
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https://www.frontiersin.org/articles/10.3389/fonc.2025.1556956/full

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