How cells integrate complex stimuli: the effect of feedback from phosphoinositides and cell shape on cell polarization and motility.

To regulate shape changes, motility and chemotaxis in eukaryotic cells, signal transduction pathways channel extracellular stimuli to the reorganization of the actin cytoskeleton. The complexity of such networks makes it difficult to understand the roles of individual components, let alone their int...

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Bibliographic Details
Main Authors: Athanasius F M Marée, Verônica A Grieneisen, Leah Edelstein-Keshet
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS Computational Biology
Online Access:https://journals.plos.org/ploscompbiol/article/file?id=10.1371/journal.pcbi.1002402&type=printable
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