Network pharmacology, experimental validation and pharmacokinetics integrated strategy to reveal pharmacological mechanism of goutengsan on methamphetamine dependence

Network pharmacology, experimental validation and pharmacokinetics integrated strategy to reveal pharmacological mechanism of goutengsan on methamphetamine dependence

BackgroundGoutengsan (GTS) is a traditional Chinese medicine formula that can improve multiple nervous system diseases, such as methamphetamine (MA) dependence. However, the mechanism how GTS treats MA dependence remains unclear. This study was aimed to investigate the action mechanism of GTS on MA...

Full description

Saved in:
Bibliographic Details
Main Authors: Han-Cheng Li, Jie-Yu Li, Xing-Chen Wang, Ming Zeng, Yang-Kai Wu, Yi-Ling Chen, Cai-Hua Kong, Ke-Lin Chen, Jie-Ru Wu, Zhi-Xian Mo, Jia-Xuan Zhang, Chang-Shun Liu
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-11-01
Series:Frontiers in Pharmacology
Subjects:
goutengsan
methamphetamine dependence
MAPK pathway
network pharmacology
pharmacokinetics
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2024.1480562/full
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2024.1480562/full

Similar Items