Determination of nine prostaglandins in the arachidonic acid metabolic pathway with UHPLC-QQQ-MS/MS and application to in vitro and in vivo inflammation models

BackgroundProstaglandins play a vital role as crucial metabolites and inflammatory indicators within the arachidonic acid (AA) metabolic pathway. Conventional assays typically focus on a single inflammatory indicator, while multi-index detection entails a large number of samples.MethodsIn this study...

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Bibliographic Details
Main Authors: Yufeng Huang, Mengxian Wang, Ziqi Yang, Xiaotong Wang, Xinxin Wang, Fan He
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-05-01
Series:Frontiers in Pharmacology
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Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2025.1595059/full
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