Daidzein-rich isoflavone aglycones inhibit 17β-hydroxysteroid dehydrogenase 1 and increase estrogen sulfotransferase in endometriosis

Daidzein-rich isoflavone aglycones inhibit 17β-hydroxysteroid dehydrogenase 1 and increase estrogen sulfotransferase in endometriosis

Objective Endometriosis is an estrogen-dependent disease wherein isoflavones interact with estrogen receptors. Daidzein-rich isoflavone aglycones (DRIAs) have been shown to inhibit cell proliferation and aromatase activity in vitro and in vivo. This study aims to investigate the effects of DRIAs on...

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Bibliographic Details
Main Authors: Yosuke Tarumi, Osamu Takaoka, Yuko Izumi, Akihisa Katayama, Koki Shimura, Hiroyuki Okimura, Hisashi Kataoka, Fumitake Ito, Izumi Kusuki, Jo Kitawaki, Taisuke Mori
Format: Article
Language:English
Published: Taylor & Francis Group 2025-12-01
Series:Gynecological Endocrinology
Subjects:
Endometriosis
estrogen synthesis
17β-hydroxysteroid dehydrogenase
estrogen sulfotransferase
isoflavones
Online Access:https://www.tandfonline.com/doi/10.1080/09513590.2025.2516202
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https://www.tandfonline.com/doi/10.1080/09513590.2025.2516202

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