Evidence for retrogene origins of the prion gene family.

The evolutionary origin of prion genes, only known to exist in the vertebrate lineage, had remained elusive until recently. Following a lead from interactome investigations of the murine prion protein, our previous bioinformatic analyses revealed the evolutionary descent of prion genes from an ances...

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Bibliographic Details
Main Authors: Sepehr Ehsani, Renzhu Tao, Cosmin L Pocanschi, Hezhen Ren, Paul M Harrison, Gerold Schmitt-Ulms
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0026800&type=printable
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