Revolutionizing diabetes treatment: computational insights into 4-hydroxy isoleucine derivatives and advanced molecular screening for antidiabetic compounds
Aim: This study aimed to computationally identify and optimize 4-hydroxy isoleucine (4HILe) derivatives from fenugreek as multitarget antidiabetic agents against α-glucosidase, α-amylase, and aldose reductase [PDB (protein data bank) IDs: 5NN8, 4GQR, 4QX4]. Methods: A multi-step computational workfl...
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| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Open Exploration
2025-04-01
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| Series: | Exploration of Drug Science |
| Subjects: | |
| Online Access: | https://www.explorationpub.com/uploads/Article/A1008104/1008104.pdf |
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