Genetic variants in inflammation-related genes are associated with radiation-induced toxicity following treatment for non-small cell lung cancer.

Genetic variants in inflammation-related genes are associated with radiation-induced toxicity following treatment for non-small cell lung cancer.

Treatment of non-small cell lung cancer (NSCLC) with radiotherapy or chemoradiotherapy is often accompanied by the development of esophagitis and pneumonitis. Identifying patients who might be at increased risk for normal tissue toxicity would help in determination of the optimal radiation dose to a...

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Main Authors: Michelle A T Hildebrandt, Ritsuko Komaki, Zhongxing Liao, Jian Gu, Joe Y Chang, Yuanqing Ye, Charles Lu, David J Stewart, John D Minna, Jack A Roth, Scott M Lippman, James D Cox, Waun Ki Hong, Margaret R Spitz, Xifeng Wu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-08-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0012402&type=printable
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https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0012402&type=printable

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