Beyond basic characterization and omics: Immunomodulatory roles of platelet‐derived extracellular vesicles unveiled by functional testing

Beyond basic characterization and omics: Immunomodulatory roles of platelet‐derived extracellular vesicles unveiled by functional testing

Abstract Renowned for their role in haemostasis and thrombosis, platelets are also increasingly recognized for their contribution in innate immunity, immunothrombosis and inflammatory diseases. Platelets express a wide range of receptors, which allows them to reach a variety of activation endpoints...

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Main Authors: Mari Palviainen, Johanna Puutio, Rikke Halse Østergaard, Johannes A. Eble, Katariina Maaninka, Umar Butt, Joseph Ndika, Otto K. Kari, Masood Kamali‐Moghaddam, Kasper Kjaer‐Sorensen, Claus Oxvig, Ana M. Aransay, Juan M. Falcon‐Perez, Antonio Federico, Dario Greco, Saara Laitinen, Yuya Hayashi, Pia R.‐M. Siljander
Format: Article
Language:English
Published: Wiley 2024-10-01
Series:Journal of Extracellular Vesicles
Subjects:
extracellular vesicles
functional assays
immunomodulatory
inflammation
innate immunity
macrophages
Online Access:https://doi.org/10.1002/jev2.12513
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https://doi.org/10.1002/jev2.12513

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