Characterizing dynamic interactions between ultradian glucocorticoid rhythmicity and acute stress using the phase response curve.

The hypothalamic-pituitary-adrenal (HPA) axis is a dynamic oscillatory hormone signalling system that regulates the pulsatile secretion of glucocorticoids from the adrenal glands. In addition to regulation of basal levels of glucocorticoids, the HPA axis provides a rapid hormonal response to stress...

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Bibliographic Details
Main Authors: James Rankin, Jamie J Walker, Richard Windle, Stafford L Lightman, John R Terry
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0030978&type=printable
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