TADBD: a sensitive and fast method for detection of typologically associated domain boundaries

A topologically associated domain (TAD) is a self-interacting genomic block. Detection of TAD boundaries on Hi-C contact matrix is one of the most important issues in the analysis of 3D genome architecture at TAD level. Here, we present TAD boundary detection (TADBD), a sensitive and fast computatio...

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Bibliographic Details
Main Authors: Hongqiang Lyu, Lin Li, Zhifang Wu, Tian Wang, Jiguang Zheng, Hongda Wang
Format: Article
Language:English
Published: Taylor & Francis Group 2020-07-01
Series:BioTechniques
Subjects:
Online Access:https://www.future-science.com/doi/10.2144/btn-2019-0165
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