Haemophagocytic lymphohistiocytosis: an uncommon presentation in systemic lupus erythematosus and acute leukaemia

Haemophagocytic lymphohistiocytosis: an uncommon presentation in systemic lupus erythematosus and acute leukaemia

Introduction: Haemophagocytic lymphohistiocytosis (HLH) is a rare and potentially life-threatening hyperinflammatory syndrome, characterised by uncontrolled activation of cytotoxic T lymphocytes, natural killer cells and macrophages, leading to a cytokine storm and subsequent multiorgan damage. Whil...

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Main Authors: Nada Msabri Gharbi, Alex Smithson, He Zhang Lin, Mario Mandis, Diana Carolina Quiroga Parada, Oriana Guevara Vasquez, Gloria De la Red Bellvis
Format: Article
Language:English
Published: SMC MEDIA SRL 2025-07-01
Series:European Journal of Case Reports in Internal Medicine
Subjects:
haemophagocytic lymphohistiocytosis
systemic lupus erythematosus
acute monoblastic leukaemia
macrophage activation syndrome
hyperferritinaemia
Online Access:https://www.ejcrim.com/index.php/EJCRIM/article/view/5555
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