Two-dimensional analysis of plasma-derived extracellular vesicles to determine the HER2 status in breast cancer patients

Abstract Breast cancer, one of the most common cancers in women, is classified by the expression of hormone receptors and the growth factor receptor HER2, which is important for personalised tumour treatment with HER2-targeted therapies. Tumour biopsies are required for histopathological diagnosis o...

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Main Authors: Alexis Wilhelm, Charlotte Flynn, Evelyn Hammer, Johannes Roessler, Bernhard Haller, Rudolf Napieralski, Moritz Leuthner, Sanja Tosheska, Kèvin Knoops, Anjusha Mathew, Giuliano Ciarimboli, Jan Kranich, Lavinia Flaskamp, Siobhan King, Heidrun Gevensleben, Quirin Emslander, Anna Pastucha, Mathias Reisbeck, Lukas Rief, Holger Bronger, Tobias Dreyer, Andreas R. Bausch, Andreas Pichlmair, Thomas Brocker, Reinhard Zeidler, Wolfgang Hammerschmidt, Melanie Piedavent-Salomom, Carmen López-Iglesias, Gabrielle Schricker, Oliver Haydn, Marion Kiechle, Sabine Grill, Ron Heeren, Percy A. Knolle, Olaf Wilhelm, Bastian Höchst
Format: Article
Language:English
Published: BMC 2025-06-01
Series:Breast Cancer Research
Online Access:https://doi.org/10.1186/s13058-025-02056-z
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