Exploring the cancerous nexus: the pivotal and diverse roles of USP39 in cancer development

Exploring the cancerous nexus: the pivotal and diverse roles of USP39 in cancer development

Abstract The ubiquitin–proteasome system enables post-transcriptional protein modification and is a major pathway for the degradation of most of them in eukaryotic cells. Among these, the ubiquitin-specific protease (USP) family is the most extensively studied. As an important member of the USP fami...

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Main Authors: Yujing Chen, Jingyi Zhang, Jinfeng Yang, Jiawei Zhao, Xiaotong Guo, Juzheng Zhang, Jinfeng Gan, Weijia Zhao, Siqi Chen, Xinwen Zhang, Yi Lin, Jiamin Jin
Format: Article
Language:English
Published: Springer 2025-05-01
Series:Discover Oncology
Subjects:
Ubiquitin-specific protease 39 (USP39)
Cancer
Deubiquitination
RNA splicing
Ubiquitin–proteasome system inhibitors
Online Access:https://doi.org/10.1007/s12672-025-02480-9
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https://doi.org/10.1007/s12672-025-02480-9

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