Renoprotective Effect of Pitavastatin against TAA-Induced Renal Injury: Involvement of the miR-93/PTEN/AKT/mTOR Pathway

Renoprotective Effect of Pitavastatin against TAA-Induced Renal Injury: Involvement of the miR-93/PTEN/AKT/mTOR Pathway

This research investigated if pitavastatin (Pita) might protect rats’ kidneys against thioacetamide (TAA). By altering the PTEN/AKT/mTOR pathway, pitavastatin may boost kidney antioxidant capacity and minimize oxidative damage. Statins have several benefits, including antioxidant and anti-inflammato...

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Main Authors: Marawan A. Elbaset, Bassim M. S. A. Mohamed, Passant E. Moustafa, Tuba Esatbeyoglu, Sherif M. Afifi, Alyaa F. Hessin, Sahar S. Abdelrahman, Hany M. Fayed
Format: Article
Language:English
Published: Wiley 2024-01-01
Series:Advances in Pharmacological and Pharmaceutical Sciences
Online Access:http://dx.doi.org/10.1155/2024/6681873
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http://dx.doi.org/10.1155/2024/6681873

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