Novel insights into the molecular mechanisms of sepsis-associated acute kidney injury: an integrative study of GBP2, PSMB8, PSMB9 genes and immune microenvironment characteristics

Novel insights into the molecular mechanisms of sepsis-associated acute kidney injury: an integrative study of GBP2, PSMB8, PSMB9 genes and immune microenvironment characteristics

Abstract Background Sepsis-associated acute kidney injury (SA-AKI) is a prevalent and severe complication of sepsis, but its complex pathogenesis remains unclear. This study aims to identify potential biomarkers for SA-AKI by elucidating its molecular mechanisms through bioinformatics methods. Metho...

Full description

Saved in:
Bibliographic Details
Main Authors: Haiting Ye, Xiang Zhang, Pengyan Li, Mei Wang, Ruolan Liu, Dingping Yang
Format: Article
Language:English
Published: BMC 2025-03-01
Series:BMC Nephrology
Subjects:
Sepsis-associated acute kidney injury
Bioinformatics
LASSO
WGCNA
Immune infiltration
Online Access:https://doi.org/10.1186/s12882-025-04069-4
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

https://doi.org/10.1186/s12882-025-04069-4

Similar Items