Case Report: Neurofilament light chain in the follow up of progressive multifocal leukoencephalopathy in a patient with multiple sclerosis treated with ocrelizumab

Case Report: Neurofilament light chain in the follow up of progressive multifocal leukoencephalopathy in a patient with multiple sclerosis treated with ocrelizumab

Progressive multifocal leukoencephalopathy (PML) results from the reactivation of John Cunningham virus JC virus and is a rare complication of anti-CD20 drug therapy. Neurofilament light chains increasingly serve as a marker of neuroaxonal damage in the follow-up of patients with multiple sclerosis...

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Bibliographic Details
Main Authors: Raquel Piñar-Morales, Raquel Calle-Calle, Maria Carrasco-Garcia, Cristina Davila-Arias, Luisa Maria Villar-Guimerans, Francisco J. Barrero Hernandez
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-04-01
Series:Frontiers in Pharmacology
Subjects:
John Cunningham virus
multiple sclerosis
neurofilament light chain
ocrelizumab
progressive multifocal leukoencephalopathy
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2025.1571699/full
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https://www.frontiersin.org/articles/10.3389/fphar.2025.1571699/full

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