Exercise training partly ameliorates cardiac dysfunction in mice during doxorubicin treatment of breast cancer

Exercise training partly ameliorates cardiac dysfunction in mice during doxorubicin treatment of breast cancer

Abstract Introduction Doxorubicin is a chemotherapeutic drug used to treat various cancers. Exercise training (ET) can attenuate some cardiotoxic effects of doxorubicin (DOX) in tumor-free animals. However, the ET effects on cardiac function and glucose metabolism in DOX-treated breast cancer models...

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Main Authors: Tytti-Maria Uurasmaa, Pauline Bourdin, Wail Nammas, Shiva Latifi, Heidi Liljenbäck, Antti Saraste, Olli Eskola, Johan Rajander, Anne Roivainen, Helene Rundqvist, Anu Autio, Ilkka Heinonen, Katja Anttila
Format: Article
Language:English
Published: BMC 2025-01-01
Series:Journal of Translational Medicine
Subjects:
Glucose metabolism
Cardiotoxicity
Exercise
Anthracyclines
CS
LDH
Online Access:https://doi.org/10.1186/s12967-025-06108-y
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https://doi.org/10.1186/s12967-025-06108-y

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