SULT2B1: a novel therapeutic target in colorectal cancer via modulation of AKT/PKM2-mediated glycolysis and proliferation

SULT2B1: a novel therapeutic target in colorectal cancer via modulation of AKT/PKM2-mediated glycolysis and proliferation

Abstract Background Sulfotransferase family 2B member 1 (SULT2B1) is involved in regulating cell proliferation, migration and metabolism. However, there is still dispute regarding whether SULT2B1 acts as an oncogene or a suppressor, and the intrinsic mechanisms in modulating tumor progression need t...

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Bibliographic Details
Main Authors: Jianxing Ma, Fengyao Sun, Wen Li, Ruihang Du, Mingchan Liu, Qiuya Wei, Boxiong Kang, Siyuan Yan, Chen Wang
Format: Article
Language:English
Published: BMC 2024-12-01
Series:Journal of Translational Medicine
Subjects:
SULT2B1
Colorectal cancer
Cell proliferation
AKT signaling pathway
PKM2
Online Access:https://doi.org/10.1186/s12967-024-05910-4
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https://doi.org/10.1186/s12967-024-05910-4

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