The developing role of NRF2 and HMOX1 in treatment response of cutaneous leishmaniasis

The developing role of NRF2 and HMOX1 in treatment response of cutaneous leishmaniasis

Abstract Anthroponotic cutaneous leishmaniasis (ACL), a neglected parasitic disease, created significant treatment challenges due to rising antimonial resistance, particularly in endemic regions like Iran. This study aimed to investigate the mechanisms behind treatment unresponsiveness in ACL patien...

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Bibliographic Details
Main Authors: Niloofar Mehrolhasani, Mahsa Faramarzpour, Ehsan Salarkia, Alireza Keyhani, Shahriar Dabiri, Simin Shamsi Meymandi
Format: Article
Language:English
Published: Nature Portfolio 2025-04-01
Series:Scientific Reports
Subjects:
Leishmania
MicroRNA
L. tropica
Drug unresponsiveness
NRF2
HMOX1
Online Access:https://doi.org/10.1038/s41598-025-99456-0
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https://doi.org/10.1038/s41598-025-99456-0

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