Protocol for isolation and transplantation of rat pancreatic islets in the kidney capsule to treat diabetes

Summary: Islet transplantation offers promise for those with type 1 and late-stage type 2 diabetes; however, islet isolation from the pancreas is challenging due to the interference of exocrine tissue. We describe steps for constructing a diabetes model and precise islet isolation by a perfusion-bas...

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Bibliographic Details
Main Authors: Dayan Li, Weijing Kong, Yi Hong, Wei Zhang, Bingbing Sun, Xi Wang, Kai Wang
Format: Article
Language:English
Published: Elsevier 2025-03-01
Series:STAR Protocols
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Online Access:http://www.sciencedirect.com/science/article/pii/S2666166724006518
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