Adenovirus vectors can infect mouse megakaryocytes – implications for vaccine-induced thrombosis/thrombocytopenia

Background: Adenoviruses, adenoviral vector vaccines, and gene delivery systems have been implicated in thrombosis/thrombocytopenia syndrome. The underlying cause remains unknown. We have previously hypothesized that infection of megakaryocytes (MKs), the progenitor cells of platelets, plays a centr...

Full description

Saved in:
Bibliographic Details
Main Authors: Simon Collett, Linda Earnest, Melissa A. Edeling, Ashley Huey Yiing Yap, Julio Carrera Montoya, Chantal Attard, Ladina Di Rago, Alison Farley, Ashley P. Ng, Paul Monagle, Joseph Torresi
Format: Article
Language:English
Published: Elsevier 2025-05-01
Series:Research and Practice in Thrombosis and Haemostasis
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S247503792500233X
Tags: Add Tag
No Tags, Be the first to tag this record!