EPS8L2 drives colorectal cancer cell proliferation and migration via YBX1-dependent activation of G3BP2 transcription
Abstract Colorectal cancer (CRC) remains a leading cause of cancer-related mortality worldwide, characterized by molecular heterogeneity and limited therapeutic options. Here, we identified EPS8L2 as a novel driver of colorectal tumorigenesis. EPS8L2 is significantly upregulated in CRC tissues and n...
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| Main Authors: | Yimeng Duan, Peixian Li, Yanmei Yang, Guanghua Wu, Hao Xing, Hong Chen, Liangbo Zhao, Lei Liu, Xiao Sun, Shuiling Jin, Luyun He, Benyu Liu |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Publishing Group
2025-08-01
|
| Series: | Cell Death and Disease |
| Online Access: | https://doi.org/10.1038/s41419-025-07929-x |
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