Home cage-based insights into motor learning and strategy adaptation in a Huntington disease mouse model.

Huntington disease (HD) is a genetic neurodegenerative disorder characterized by progressive motor dysfunction, cognitive decline, and neuropsychiatric symptoms. Assessing early motor skill deficits in HD mouse models is challenging with traditional behavioral tasks. This study uses a home cage-base...

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Bibliographic Details
Main Authors: Daniel Ramandi, Marja D Sepers, Zefang Wang, Brian Han, Cameron L Woodard, Timothy H Murphy, Lynn A Raymond
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2025-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0318663
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