The Spleen Plays No Role in Nephrotoxic Serum Nephritis, but Constitutes a Place of Compensatory Haematopoiesis.

The Spleen Plays No Role in Nephrotoxic Serum Nephritis, but Constitutes a Place of Compensatory Haematopoiesis.

<h4>Background</h4>The spleen has been implicated in the pathogenesis of immune-complex glomerulonephritis by initiating and resolving adaptive immune responses. Thus, we aimed to evaluate the role of the spleen in experimental nephrotoxic serum nephritis (NTS).<h4>Methods</h4&g...

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Main Authors: Katharina Artinger, Alexander H Kirsch, Ida Aringer, Corinna Schabhüttl, Alexander R Rosenkranz, Philipp Eller, Elena Rho, Kathrin Eller
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0135087&type=printable
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https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0135087&type=printable

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