Hydroxychloroquine sulfate for IgA nephropathy: mechanisms and therapeutic potential in improving proteinuria and alleviating disease progression - a literature review

Hydroxychloroquine sulfate for IgA nephropathy: mechanisms and therapeutic potential in improving proteinuria and alleviating disease progression - a literature review

Abstract IgA nephropathy (IgAN), the most common form of glomerulonephritis worldwide, often progresses to chronic kidney failure within 10 to 15 years. Despite its clinical importance, effective disease-modifying therapies for IgAN remain limited. Proteinuria is well recognized as both a prognostic...

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Bibliographic Details
Main Authors: Liao Yilei, Du Yating, Fang Yaxuan, Liu Chenxuan, Cheng Tingzhu, Li Jinpu, Rao Xiangrong, Guo Chuan
Format: Article
Language:English
Published: BMC 2025-07-01
Series:BMC Nephrology
Subjects:
IgA nephropathy
Proteinuria
Hydroxychloroquine
Galactose-deficient IgA1
Mechanism
Online Access:https://doi.org/10.1186/s12882-025-04262-5
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https://doi.org/10.1186/s12882-025-04262-5

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