ACSM2B rs73530508 polymorphism affects susceptibility to esophageal cancer by regulating indolepropionic acid levels

ACSM2B rs73530508 polymorphism affects susceptibility to esophageal cancer by regulating indolepropionic acid levels

Background: Tryptophan metabolism is involved in esophageal carcinogenesis. However, its genetic mechanisms remain unclear. This study aimed to investigate the effect of genetic variants that encode tryptophan metabolism on susceptibility to esophageal cancer (EC) and elucidate the mechanisms underl...

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Bibliographic Details
Main Authors: Yun Chen, Ruijun Lin, Qianhua Luo, Tao Liu, Xiaoyan Li, Danling Zheng, Siman Su, Meini Chen, Jianxiang Huang, Yihui Huang, Shuyao Zhang
Format: Article
Language:English
Published: Elsevier 2025-05-01
Series:Cancer Pathogenesis and Therapy
Subjects:
Esophageal cancer
Susceptibility
ACSM2B rs73530508
Indolepropionic acid
Tryptophan metabolism
Online Access:http://www.sciencedirect.com/science/article/pii/S2949713224000752
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