Mapping growth differentiation factor-15 (GDF15)-mediated signaling pathways in cancer: insights into its role across different cancer types

Mapping growth differentiation factor-15 (GDF15)-mediated signaling pathways in cancer: insights into its role across different cancer types

Abstract Growth differentiation factor-15 (GDF15) is a cytokine/growth factor that belongs to the Transforming growth factor-ß (TGF-ß) protein family. The expression of GDF15 is low in most human organs under normal conditions. GDF15 is a stress-responsive cytokine primarily produced by macrophages...

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Main Authors: Akhila Balakrishna Rai, Jalaluddin Akbar Kandel Codi, Giridhara Prema Suchitha, Kadabagere Narayanaswamy Hemavathi, Shobha Dagamajalu, Chandran S. Abhinand, Rajesh Raju, Thottethodi Subrahmanya Keshava Prasad
Format: Article
Language:English
Published: Springer 2025-03-01
Series:Discover Oncology
Subjects:
GDF15
Cancer
Signaling pathway
Data mining
Bioinformatics
Molecular interactions
Online Access:https://doi.org/10.1007/s12672-025-02121-1
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https://doi.org/10.1007/s12672-025-02121-1

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