Diverse single-stranded nucleic acid binding proteins enable both stable protection and rapid exchange required for biological function

Diverse single-stranded nucleic acid binding proteins enable both stable protection and rapid exchange required for biological function

Single-stranded nucleic acid (ssNA) binding proteins must both stably protect ssNA transiently exposed during replication and other NA transactions, and also rapidly reorganize and dissociate to allow further NA processing. How these seemingly opposing functions can coexist has been recently elucida...

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Bibliographic Details
Main Authors: Michael Morse, Ben A. Cashen, Ioulia Rouzina, Mark C. Williams
Format: Article
Language:English
Published: Cambridge University Press 2025-01-01
Series:QRB Discovery
Subjects:
optical tweezers
protein–nucleic acid interactions
single molecule biophysics
Online Access:https://www.cambridge.org/core/product/identifier/S2633289224000218/type/journal_article
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https://www.cambridge.org/core/product/identifier/S2633289224000218/type/journal_article

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