Combined immunohistochemistry of PRAME and p16 in the differentiation of melanocytic neoplasms, with a detailed focus on acral lesions

Combined immunohistochemistry of PRAME and p16 in the differentiation of melanocytic neoplasms, with a detailed focus on acral lesions

Abstract Background Isolated immunohistochemical indicators are limited to diagnose melanocytic neoplasms. This retrospective study is to assess the diagnostic value of combined immunohistochemical analysis targeting preferentially expressed antigen in melanoma (PRAME) and p16 in melanocytic neoplas...

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Bibliographic Details
Main Authors: Jingwei Zheng, Jie Zang, Qiuju Miao, Xuebao Shao, Hao Song, Xiaopo Wang, Ying Zhang, Hao Chen
Format: Article
Language:English
Published: BMC 2024-12-01
Series:Diagnostic Pathology
Subjects:
Melanoma (MM)
Melanocytic nevus
PRAME
p16
Immunohistochemistry(IHC)
Online Access:https://doi.org/10.1186/s13000-024-01586-y
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https://doi.org/10.1186/s13000-024-01586-y

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