Novel 4-alkoxy Meriolin Congeners Potently Induce Apoptosis in Leukemia and Lymphoma Cells

Novel 4-alkoxy Meriolin Congeners Potently Induce Apoptosis in Leukemia and Lymphoma Cells

<i>Meriolins</i> (3-(pyrimidin-4-yl)-7-azaindoles) are synthetic hybrids of the naturally occurring alkaloids <i>variolin</i> and <i>meridianin</i> and display a strong cytotoxic potential. We have recently shown that the novel derivative <i>meriolin</i&g...

Full description

Saved in:
Bibliographic Details
Main Authors: Karina S. Krings, Tobias R. Wassenberg, Pablo Cea-Medina, Laura Schmitt, Ilka Lechtenberg, Tanya R. Llewellyn, Nan Qin, Holger Gohlke, Sebastian Wesselborg, Thomas J. J. Müller
Format: Article
Language:English
Published: MDPI AG 2024-12-01
Series:Molecules
Subjects:
apoptosis inducers
7-azaindoles
biheteroaryls
cyclin dependent kinases (CDK)
leukemia cell lines
lymphoma cell lines
Online Access:https://www.mdpi.com/1420-3049/29/24/6050
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

https://www.mdpi.com/1420-3049/29/24/6050

Similar Items