GABP Promotes Mesangial Cell Proliferation and Renal Fibrosis Through GLI1 in Diabetic Nephropathy

GABP Promotes Mesangial Cell Proliferation and Renal Fibrosis Through GLI1 in Diabetic Nephropathy

Abstract Abnormal proliferation of mesangial cells is a hallmark of diabetic nephropathy (DN). However, the cellular signaling mechanisms that regulate this proliferation remain poorly understood. In this study, it is demonstrated that GA‐binding protein (GABP), a member of the ETS family of transcr...

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Main Authors: Lei Du, Sijie Liu, Yinfei Lu, Dongxue Ren, Xiujuan Yu, Yue Hu, Tingting Yang, Qun Yang, Jingxian Ming, Jiawei Zhang, Xiaoxing Yin, Qian Lu
Format: Article
Language:English
Published: Wiley 2025-04-01
Series:Advanced Science
Subjects:
diabetic nephropathy
GABP
GLI1
mesangial cell proliferation
renal fibrosis
Online Access:https://doi.org/10.1002/advs.202407462
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https://doi.org/10.1002/advs.202407462

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