Defining decision thresholds for judgments on health benefits and harms using the Grading of Recommendations Assessment, Development and Evaluation (GRADE) Evidence to Decision (EtD) frameworks: a protocol for a randomised methodological study (GRADE-THRESHOLD)

Defining decision thresholds for judgments on health benefits and harms using the Grading of Recommendations Assessment, Development and Evaluation (GRADE) Evidence to Decision (EtD) frameworks: a protocol for a randomised methodological study (GRADE-THRESHOLD)

Introduction The Grading of Recommendations Assessment, Development and Evaluation (GRADE) and similar Evidence to Decision (EtD) frameworks require its users to judge how substantial the effects of interventions are on desirable and undesirable people-important health outcomes. However, decision th...

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Main Authors: Pablo Alonso-Coello, Lawrence Mbuagbaw, Elena Parmelli, Feng Xie, Holger J Schünemann, Antonio Bognanni, Nancy Santesso, Wojtek Wiercioch, Elie A Akl, Thomas Piggott, Uwe Siebert, Ilse M Verstijnen, Andrea J Darzi, Jan L Brozek, Gian Paolo Morgano, Zuleika Saz-Parkinson
Format: Article
Language:English
Published: BMJ Publishing Group 2022-03-01
Series:BMJ Open
Online Access:https://bmjopen.bmj.com/content/12/3/e053246.full
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