Time course of organ and hematological response to complement blockage in transplant-associated thrombotic microangiopathy after allogeneic hematopoietic stem cell transplantation

Time course of organ and hematological response to complement blockage in transplant-associated thrombotic microangiopathy after allogeneic hematopoietic stem cell transplantation

BackgroundHematopoietic stem cell transplantation (HSCT) offers a potential cure for various hematologic malignancies and non-malignant disorders but is often accompanied by severe complications, one of the most challenging being transplant-associated thrombotic microangiopathy (TA-TMA). Eculizumab,...

Full description

Saved in:
Bibliographic Details
Main Authors: Tatiana A. Rudakova, Julia Yu Vlasova, Olesya V. Paina, Olga A. Slesarchuk, Marina A. Gorodnova, Tatiana S. Schegoleva, Oleg V. Goloshchapov, Tatiana A. Bykova, Elena V. Morozova, Lyudmila S. Zubarovskaya, Ivan S. Moiseev, Alexander D. Kulagin
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-03-01
Series:Frontiers in Medicine
Subjects:
hematopoietic cell transplantation
early complications
transplantation-associated thrombotic microangiopathy
complement inhibition
eculizumab
Online Access:https://www.frontiersin.org/articles/10.3389/fmed.2025.1551066/full
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

https://www.frontiersin.org/articles/10.3389/fmed.2025.1551066/full

Similar Items