Comparative genomics search for losses of long-established genes on the human lineage.

Taking advantage of the complete genome sequences of several mammals, we developed a novel method to detect losses of well-established genes in the human genome through syntenic mapping of gene structures between the human, mouse, and dog genomes. Unlike most previous genomic methods for pseudogene...

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Bibliographic Details
Main Authors: Jingchun Zhu, J Zachary Sanborn, Mark Diekhans, Craig B Lowe, Tom H Pringle, David Haussler
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2007-12-01
Series:PLoS Computational Biology
Online Access:https://journals.plos.org/ploscompbiol/article/file?id=10.1371/journal.pcbi.0030247&type=printable
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