STUDY OF THE DNA DAMAGE IN HeLa CELLS EXPOSED TO THE COMBINATION OF ULTRASOUND AND 5-FLUORURACYL

STUDY OF THE DNA DAMAGE IN HeLa CELLS EXPOSED TO THE COMBINATION OF ULTRASOUND AND 5-FLUORURACYL

To understand the mechanism of the effect of 5 % 5-fluorouracil (5-FU) gel used simultaneously with ultrasound (US ) on a tumor in patients with cervical cancer, the level of DNA damage was studied in vitro. We used cervical adenocarcinoma HeLa CC L-2 cells cultured under standard conditions in RPMI...

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Bibliographic Details
Main Authors: E. M. Frantsiyants, E. I. Surikova, I. A. Goroshinskaya, T. I. Moiseenko, N. A. Nazaralieva, D. S. Potemkin, N. G. Vasilchenko
Format: Article
Language:Russian
Published: Russian Academy of Sciences, Tomsk National Research Medical Center 2019-11-01
Series:Сибирский онкологический журнал
Subjects:
dna damage
dna comets
hela culture
5-fluorouracil
ultrasound
chemoresistance
cervical cancer
Online Access:https://www.siboncoj.ru/jour/article/view/1190
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