A large-scale benchmark for network inference from single-cell perturbation data
Abstract Mapping biological mechanisms in cellular systems is a fundamental step in early-stage drug discovery that serves to generate hypotheses on what disease-relevant molecular targets may effectively be modulated by pharmacological interventions. With the advent of high-throughput methods for m...
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| Main Authors: | Mathieu Chevalley, Yusuf H. Roohani, Arash Mehrjou, Jure Leskovec, Patrick Schwab |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2025-03-01
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| Series: | Communications Biology |
| Online Access: | https://doi.org/10.1038/s42003-025-07764-y |
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