A large-scale benchmark for network inference from single-cell perturbation data

Abstract Mapping biological mechanisms in cellular systems is a fundamental step in early-stage drug discovery that serves to generate hypotheses on what disease-relevant molecular targets may effectively be modulated by pharmacological interventions. With the advent of high-throughput methods for m...

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Bibliographic Details
Main Authors: Mathieu Chevalley, Yusuf H. Roohani, Arash Mehrjou, Jure Leskovec, Patrick Schwab
Format: Article
Language:English
Published: Nature Portfolio 2025-03-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-025-07764-y
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