Anticonvulsant Potential and Toxicological Profile of <i>Verbesina persicifolia</i> Leaf Extracts: Evaluation in Zebrafish Seizure and <i>Artemia salina</i> Toxicity Models

Anticonvulsant Potential and Toxicological Profile of <i>Verbesina persicifolia</i> Leaf Extracts: Evaluation in Zebrafish Seizure and <i>Artemia salina</i> Toxicity Models

Epilepsy is a chronic neurological disorder with significant treatment challenges, necessitating the search for alternative therapies. This study evaluates the anticonvulsant activity and toxicological profile of <i>Verbesina persicifolia</i> leaf extracts. Methanolic and sequential frac...

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Main Authors: Carlos Alberto López-Rosas, Santiago González-Periañez, Tushar Janardan Pawar, Jorge Iván Zurutuza-Lorméndez, Fernando Rafael Ramos-Morales, José Luís Olivares-Romero, Margarita Virginia Saavedra Vélez, Fabiola Hernández-Rosas
Format: Article
Language:English
Published: MDPI AG 2025-04-01
Series:Plants
Subjects:
<i>Verbesina persicifolia</i>
anticonvulsant activity
zebrafish epilepsy model
PTZ-induced seizures
<i>Artemia salina</i> toxicity
GABAergic modulation
Online Access:https://www.mdpi.com/2223-7747/14/7/1078
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