A benzimidazole derivative as an effective antitumor agent in terms of syngeneic lung tumors and melanoma treatment

A benzimidazole derivative as an effective antitumor agent in terms of syngeneic lung tumors and melanoma treatment

Purpose of the study. Evaluation of the effect of the benzimidazole derivative dihydrobromide‑2-(3,4‑dihydroxyphenyl)- 9‑diethylamino-ethylimidazo-[ 1,2‑a] benzimidazole (RU‑185) on the growth of Lewis lung epidermoid carcinoma and B16-F10 melanoma when administered intragastrically.Materials and me...

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Main Authors: E. F. Komarova, A. S. Morkovnik, O. N. Zhukovskaya, E. V. Verenikina, N. A. Shevchenko, D. V. Khodakova, L. Z. Kurbanova, M. V. Mindar, E. V. Zaikina, A. V. Galina
Format: Article
Language:Russian
Published: ANO "Perspective of oncology" 2022-03-01
Series:Южно-Российский онкологический журнал
Subjects:
dihydrobromide-2-(3
4-dihydroxyphenyl)-9-diethylamino-ethylimidazo-[1
2-a] benzimidazole
lewis lung carcinoma
melanoma b16-f10
antitumor efficacy
intragastric administration
Online Access:https://www.cancersp.com/jour/article/view/151
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