Elucidating structural variability in p53 conformers using combinatorial refinement strategies and molecular dynamics

Low molecular weight proteins and protein assemblies can now be investigated using cryo-electron microscopy (EM) as a complement to traditional structural biology techniques. It is important, however, to not lose sight of the dynamic information inherent in macromolecules that give rise to their exq...

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Bibliographic Details
Main Authors: Deborah F. Kelly, Maria J. Solares, William J. Dearnaley
Format: Article
Language:English
Published: Taylor & Francis Group 2024-12-01
Series:Cancer Biology & Therapy
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Online Access:https://www.tandfonline.com/doi/10.1080/15384047.2023.2290732
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