Adjuvant Use of Ivabradine in Acute Heart Failure due to Myocarditis
We report two cases of young men in whom acute heart failure due to myocarditis was diagnosed. The patients had been transferred to the intensive care unit (ICU) with commencing symptoms of acute heart failure and consecutive multiorgan failure for further treatment and to evaluate the indication fo...
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| Format: | Article |
| Language: | English |
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Wiley
2011-01-01
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| Series: | Case Reports in Medicine |
| Online Access: | http://dx.doi.org/10.1155/2011/203690 |
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| author | Jennifer Franke Dorothee Schmahl Stephanie Lehrke Regina Pribe Raffi Bekeredjian Andreas O. Doesch Philipp Ehlermann Philipp Schnabel Hugo A. Katus Christian Zugck |
| author_facet | Jennifer Franke Dorothee Schmahl Stephanie Lehrke Regina Pribe Raffi Bekeredjian Andreas O. Doesch Philipp Ehlermann Philipp Schnabel Hugo A. Katus Christian Zugck |
| author_sort | Jennifer Franke |
| collection | DOAJ |
| description | We report two cases of young men in whom acute heart failure due to myocarditis was diagnosed. The patients had been transferred to the intensive care unit (ICU) with commencing symptoms of acute heart failure and consecutive multiorgan failure for further treatment and to evaluate the indication for implantation of a ventricular assist device or for high urgent orthotopic heart transplantation. In both patients, the If-channel inhibitor ivabradine was administered off-label to provide selective heart rate reduction, and thus support hemodynamic stabilization. Though currently considered off-label use in patients suffering from severe hypotension and acute heart failure, the use of ivabradine may beneficially influence outcome by allowing optimization of the patient's heart rate concomitant to initial measures of clinical stabilization. |
| format | Article |
| id | doaj-art-cee0b5a9ea8946ab836edaf881e93a22 |
| institution | Kabale University |
| issn | 1687-9627 1687-9635 |
| language | English |
| publishDate | 2011-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Medicine |
| spelling | doaj-art-cee0b5a9ea8946ab836edaf881e93a222025-02-03T01:10:06ZengWileyCase Reports in Medicine1687-96271687-96352011-01-01201110.1155/2011/203690203690Adjuvant Use of Ivabradine in Acute Heart Failure due to MyocarditisJennifer Franke0Dorothee Schmahl1Stephanie Lehrke2Regina Pribe3Raffi Bekeredjian4Andreas O. Doesch5Philipp Ehlermann6Philipp Schnabel7Hugo A. Katus8Christian Zugck9Department of Cardiology, University of Heidelberg, Im Neuenheimer Feld 410, 69120 Heidelberg, GermanyDepartment of Cardiology, University of Heidelberg, Im Neuenheimer Feld 410, 69120 Heidelberg, GermanyDepartment of Cardiology, University of Heidelberg, Im Neuenheimer Feld 410, 69120 Heidelberg, GermanyDepartment of Cardiology, University of Heidelberg, Im Neuenheimer Feld 410, 69120 Heidelberg, GermanyDepartment of Cardiology, University of Heidelberg, Im Neuenheimer Feld 410, 69120 Heidelberg, GermanyDepartment of Cardiology, University of Heidelberg, Im Neuenheimer Feld 410, 69120 Heidelberg, GermanyDepartment of Cardiology, University of Heidelberg, Im Neuenheimer Feld 410, 69120 Heidelberg, GermanyInstitute of Pathology, University of Heidelberg, 69120 Heidelberg, GermanyDepartment of Cardiology, University of Heidelberg, Im Neuenheimer Feld 410, 69120 Heidelberg, GermanyDepartment of Cardiology, University of Heidelberg, Im Neuenheimer Feld 410, 69120 Heidelberg, GermanyWe report two cases of young men in whom acute heart failure due to myocarditis was diagnosed. The patients had been transferred to the intensive care unit (ICU) with commencing symptoms of acute heart failure and consecutive multiorgan failure for further treatment and to evaluate the indication for implantation of a ventricular assist device or for high urgent orthotopic heart transplantation. In both patients, the If-channel inhibitor ivabradine was administered off-label to provide selective heart rate reduction, and thus support hemodynamic stabilization. Though currently considered off-label use in patients suffering from severe hypotension and acute heart failure, the use of ivabradine may beneficially influence outcome by allowing optimization of the patient's heart rate concomitant to initial measures of clinical stabilization.http://dx.doi.org/10.1155/2011/203690 |
| spellingShingle | Jennifer Franke Dorothee Schmahl Stephanie Lehrke Regina Pribe Raffi Bekeredjian Andreas O. Doesch Philipp Ehlermann Philipp Schnabel Hugo A. Katus Christian Zugck Adjuvant Use of Ivabradine in Acute Heart Failure due to Myocarditis Case Reports in Medicine |
| title | Adjuvant Use of Ivabradine in Acute Heart Failure due to Myocarditis |
| title_full | Adjuvant Use of Ivabradine in Acute Heart Failure due to Myocarditis |
| title_fullStr | Adjuvant Use of Ivabradine in Acute Heart Failure due to Myocarditis |
| title_full_unstemmed | Adjuvant Use of Ivabradine in Acute Heart Failure due to Myocarditis |
| title_short | Adjuvant Use of Ivabradine in Acute Heart Failure due to Myocarditis |
| title_sort | adjuvant use of ivabradine in acute heart failure due to myocarditis |
| url | http://dx.doi.org/10.1155/2011/203690 |
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